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pentobarbital will lessen the level or result of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Steer clear of coadministration of lefamulin with solid or moderate CYP3A inducers Except the reward outweighs threats. Observe for diminished efficacy.Phenytoin and barbiturate blood amounts really sho